Richard R Tidwell Selected Research

furamidine (DB75)

11/2006	Roles for the Trypanosoma brucei P2 transporter in DB75 uptake and resistance.
6/2006	Accumulation and intracellular distribution of antitrypanosomal diamidine compounds DB75 and DB820 in African trypanosomes.
10/2004	DB75, a novel trypanocidal agent, disrupts mitochondrial function in Saccharomyces cerevisiae.
7/2004	Distribution and quantitation of the anti-trypanosomal diamidine 2,5-bis(4-amidinophenyl)furan (DB75) and its N-methoxy prodrug DB289 in murine brain tissue.
4/2004	Metabolites of an orally active antimicrobial prodrug, 2,5-bis(4-amidinophenyl)furan-bis-O-methylamidoxime, identified by liquid chromatography/tandem mass spectrometry.

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Richard R Tidwell Research Topics

Disease

17	African Trypanosomiasis (Nagana) 02/2020 - 01/2002
5	Trypanosomiasis 02/2016 - 06/2006
4	Pneumocystis Pneumonia (Pneumocystis carinii Pneumonia) 01/2008 - 01/2002
3	Body Weight (Weight, Body) 07/2014 - 12/2009
3	Visceral Leishmaniasis (Kala Azar) 12/2010 - 08/2009
2	Cardiac Arrhythmias (Arrythmia) 01/2017 - 07/2013
2	Infections 07/2014 - 01/2012
2	Parasitemia 07/2014 - 08/2009
2	Malaria 05/2009 - 10/2004
2	Acquired Immunodeficiency Syndrome (AIDS) 07/2004 - 07/2002
1	Neglected Diseases 02/2020
1	Glomerulonephritis 02/2016
1	Central Nervous System Infections (Central Nervous System Infection) 08/2014
1	Parasitic Diseases (Parasitic Disease) 07/2011
1	Leishmaniasis 04/2007
1	Pneumonia (Pneumonitis) 10/2004

Drug/Important Bio-Agent (IBA)

11	Pentamidine (NebuPent)FDA LinkGeneric 02/2016 - 06/2006
10	Pharmaceutical PreparationsIBA 02/2020 - 01/2002
7	ProdrugsIBA 02/2015 - 07/2004
5	pafuramidineIBA 02/2016 - 07/2004
5	furamidine (DB75)IBA 11/2006 - 04/2004
4	furanIBA 01/2014 - 05/2009
3	Amphotericin B (Amphotericin)FDA LinkGeneric 12/2010 - 08/2009
2	N- methoxy- 6- (5- (4- (N- methoxyamidino)phenyl)furan- 2- yl)nicotinamidineIBA 01/2014 - 01/2012
2	DiminazeneIBA 07/2011 - 12/2009
1	homidium chlorideIBA 01/2017
1	Urea (Carbamide)FDA LinkGeneric 01/2017
1	Ion Channels (Ion Channel)IBA 01/2017
1	isometamidium chloride (ISMM)IBA 01/2017
1	AminesIBA 01/2017
1	diminazene aceturateIBA 01/2017
1	CPD0905IBA 08/2014
1	benzonidazole (benznidazole)IBA 07/2014
1	Proteins (Proteins, Gene)FDA Link 07/2013
1	Eflornithine (Ornidyl)FDA Link 01/2012
1	NifurtimoxIBA 01/2012
1	diphenyl (biphenyl)IBA 07/2011
1	liposomal amphotericin B FDA Link 03/2010
1	Suramin (Suramin Sodium)IBA 12/2009
1	quinapyramineIBA 12/2009
1	Melarsoprol (Mel B)IBA 11/2008
1	CarbamatesIBA 01/2008
1	amidoximeIBA 11/2006
1	Anti-Infective Agents (Microbicides)IBA 04/2004
1	Zidovudine (Retrovir)FDA LinkGeneric 07/2002
1	amprenavir (Agenerase)FDA Link 07/2002
1	Lamivudine (Epivir)FDA Link 07/2002
1	NucleosidesIBA 07/2002

Therapy/Procedure

2	Drug Therapy (Chemotherapy) 02/2015 - 04/2007
2	Therapeutics 01/2012 - 08/2009
1	Oral Administration 08/2009